Mutations in C-C chemokine receptor type 5 (CCR5) in South African individuals
نویسندگان
چکیده
منابع مشابه
Mutations in C-C chemokine receptor type 5 (CCR5) in South African individuals.
BACKGROUND The importance of the C-C chemokine receptor type 5 (CCR5) in HIV infection and disease progression was recognized with the discovery of the Δ32 allele. Individuals homozygous for this mutation lack functional CCR5, and are almost completely resistant to HIV infection. Heterozygous individuals display decreased cell surface CCR5, which slows disease progression. Phenotypic expression...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2013
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2013.06.009